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New nerve block may slash opioid use in gallbladder surgery

NCT ID NCT06869837

Symptom relief Sponsor: Samsun University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a nerve block called the external oblique intercostal plane block could reduce the amount of opioid painkiller needed during laparoscopic gallbladder removal. 80 adults having elective surgery received the block before the procedure. Researchers measured opioid use and pain scores afterward to see if the block improved pain control and recovery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
external oblique intercostal plane block (nerve block with local anesthetic)
What this could lead to
If effective, this nerve block could reduce the need for strong painkillers during gallbladder surgery, leading to fewer side effects and faster recovery.
What could go wrong
This is a small, completed study with 80 participants. The nerve block may not work for everyone, and there is a small risk of allergic reaction or bleeding at the injection site.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

80 people

The number who actually took part.

Started

Apr 2025

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participants who will undergo elective laparoscopic cholecystectomy surgery, * Age 18-70, * ASA I-II physical status, * Body mass index (BMI) \< 35 kg/m², * Participants who have written consent to participate in the study Exclusion Criteria: * Participants with routine analgesic consumption, * Those with coagulopathy, * Those with a history of local anesthetic allergy, * Those with cardiac arrhythmia and pacemaker, * ASA III and above, Those with dementia

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Conditions

The condition(s) this trial relates to.

agnosia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Laparoscopic cholecystectomy surgery Pain management

Contacts and locations

Locations

  • Samsun University, Samsun Training and Research Hospital

    Samsun, İ̇lkadim, Turkey (Türkiye)

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