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Pain-Free lung surgery? study tests two nerve block methods

NCT ID NCT07535697

Symptom relief Sponsor: Sana Klinikum Offenbach Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two pain-relief techniques for people having minimally invasive lung surgery (VATS). One method uses ultrasound to guide a numbing injection near the spine (ESPB), done by an anesthesiologist. The other uses a camera to guide the injection between the ribs (ICNB), done by the surgeon. Researchers will track how much pain medicine patients need in the first 24 hours and their pain scores. The goal is to see which method works better for controlling pain after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Erector spinae plane block (ESPB) and intercostal nerve block (ICNB) - both are numbing injections
What this could lead to
If one method works better, it could improve pain control after lung surgery and reduce the need for strong painkillers.
What could go wrong
This is a small, early-stage study (72 people) comparing two existing techniques, so it may not show a clear winner or change practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 72 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

May 2026

An estimate. Start dates often move.

Expected to finish

May 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Provision of written informed consent * Adults (≥ 18 years of age) * Elective video-assisted thoracoscopic surgery (VATS) for pulmonary resection (e.g., lobectomy, segmentectomy, wedge resection) Exclusion Criteria: * Lack of informed consent * Language barrier * Pregnancy or breastfeeding * Known allergy to local anesthetics used in the study * Infection at the injection site(s) * History of complex chest wall surgery * Revision surgery with a prior operation within the last 6 months * Intraoperative conversion to open thoracotomy * Chronic pain syndrome * Fibromyalgia * Chronic opioid use * Chronic alcohol abuse * Chronic substance abuse (e.g., THC, amphetamines, cocaine) * History of psychiatric disorders (e.g., depression, schizophrenia) * Impaired consciousness, cognition, or ability to communicate * Known coagulopathy (including platelet count \< 80,000/µL or prolonged PTT/aPTT \>1.5× the upper limit of normal) * Ongoing therapeutic anticoagulation

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Erector spinae plane block Intercostal nerve block Regional anesthesia Video-assisted thoracoscopic surgery (VATS)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Sana Klinikum Offenbach

    RECRUITING

    Offenbach, Hesse, 63069, Germany

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