New study tests which nerve block eases gallbladder surgery pain best
NCT ID NCT07469410
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compared two types of nerve blocks for pain after laparoscopic gallbladder removal. Sixty adults received either an erector spinae plane block or a subcostal transversus abdominis plane block using the same numbing medicine. Researchers measured pain levels, need for extra painkillers, and time until first pain request to see which block works better.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- ropivacaine
- What this could lead to
- If one block proves better, it could offer a simpler, more effective way to manage pain after gallbladder surgery, especially in settings with limited resources.
- What could go wrong
- This is a small, single-center trial with only 60 patients. Results may not apply to everyone, and the blocks are compared against each other, not against no treatment or standard care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 3
Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.
- Participants
-
60 people
The number who actually took part.
- Started
-
Jun 2025
- Finished
-
Nov 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 65 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
INCLUSION CRITERIA: * Patients are both men and women. * Patients aged 18 to 65. * Patients are scheduled for a laparoscopic cholecystectomy. * Patients with ASA Physical Status I or II. Finally, III. * Give consent. EXCLUSION CRITERIA: * Hypersensitivity to local anesthesia. * Infection at the block site. * Coagulation disorders. * BMI above 40kg/m2. * Patients with pregnancy. * Converted to open surgery. * Drain placement. * Neurological or psychiatric disorders that impair cooperation. * Patients are unwilling to cooperate.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Kulsoom Mehmood
Karachi, Pakistan
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