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Hot peppers and brain freeze: scientists probe headache mysteries

NCT ID NCT03511846

First seen Feb 19, 2026 · Last updated May 20, 2026 · Updated 10 times

Summary

This study aims to find biological markers (biomarkers) for headaches like migraine and cluster headache. Researchers will use capsaicin (from chili peppers) and ice water to trigger headache-related responses in 371 participants. The goal is to better understand how these headaches work, which could lead to improved treatments in the future.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • The University of Texas Health Science Center at Houston

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.