Love hormone and buzzers tested for sunburn relief
NCT ID NCT06651476
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether giving oxytocin (a natural hormone) along with a vibrating device could raise the pain threshold in skin that had a mild sunburn. Thirty-eight healthy adults received either oxytocin or a placebo by IV, while a vibrator was applied to the sunburned area. The goal was to see if the combination made the skin less sensitive to heat pain.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- oxytocin
- What this could lead to
- If it works, this could point toward a new way to ease pain from sunburns using a combination of vibration and a hormone.
- What could go wrong
- This is a small, early-phase trial with only 38 healthy volunteers, not real sunburn patients. The results may not apply to actual sunburn pain or lead to a treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
-
38 people
The number who actually took part.
- Started
-
Dec 2024
- Finished
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Nov 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 55 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male or female \> 18 and ≤55 years of age, Body Mass Index (BMI) \<40 * Generally in good health as determined by the Principal Investigator based on prior medical history, and as assessed to be American Society of Anesthesiologists physical status 1, 2, or 3 * Fitzpatrick Scale rating I through III Exclusion Criteria: * History of skin cancer * Dark enough skin complexion that would make it infeasible to determine the minimal erythematous dose of UV-B irradiation. Anyone Fitzpatrick Scale score \>3 will be excluded * Neuropathy, chronic pain (located in any body location that is being treated), diabetes mellitus, or taking benzodiazepines or pain medications on a daily basis * Pregnancy or currently breast feeding * Subjects with current or history of ventricular tachycardia, atrial fibrillation or prolonged QT interval * Subjects with past or current history of hyponatremia or at risk for hyponatremia; anyone taking thiazide diuretics, loop diuretics, combination diuretics, lithium, carbamazepine, enalapril, Ramipril, celecoxib, temazepam, gliclazide, glimepiride, glibenclamide, glipizide, omeprazole, pantoprazole, desmopressin, SSRI's, MAOI, or the recreational drug ecstasy * Subjects with a known latex allergy
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Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Atrium Health Wake Forest Baptist Medical Center
Winston-Salem, North Carolina, 27157, United States
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