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Does menopause change the 'Love Hormone'? a study investigates

NCT ID NCT07742124

Knowledge-focused Sponsor: University Hospital, Basel, Switzerland Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 03, 2026 · Last updated Aug 25, 2026 · Updated 3 times

Summary

This study is looking at whether levels of oxytocin, often called the 'love hormone,' differ between women before and after menopause. Researchers will measure a marker of oxytocin in the blood over a month in both groups. The goal is to understand how the body's oxytocin system changes when menstrual cycles stop.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If this study finds lower oxytocin levels after menopause, it could point toward new ways to support emotional well-being and health in older women.
What could go wrong
This is a small observational study, so it can only show a link, not prove cause and effect. Results may not apply to all women.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2026

Expected to finish

Sep 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Gender is restricted to female at birht participants. Perimenopausal women and women using hormonal medication are excluded.Pregnant or lactating women were excluded due to altered oxytocin physiology and ethical considerations.

Ages

18 years and older

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Female sex at birth * Age ≥18 years Premenopausal group: • Premenopausal women aged 18-35 years with regular menstrual cycles (21-35 days) for ≥3 months prior to study entry Postmenopausal group: • Postmenopausal women ≥2 years of postmenopause (i.e. 3 years since last menstrual period (LMP), with menopause defined as ≥ 12 months of amenorrhea) Exclusion Criteria: * Pregnancy or breastfeeding * Use of hormonal contraception or hormone replacement therapy within the last 3 months * Known endocrine disorders affecting the hypothalamic-pituitary-gonadal axis * Use of medications * Severe depression (BDI score \> 28 points), any other severe psychiatric illness or acute medical disease * Inability to comply with study procedures * Participation in a trial with investigational drugs within the last 30 days

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Postmenopausal Premenopausal

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • University Hospital Basel

    RECRUITING

    Basel, Canton of Basel-City, 4031, Switzerland

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