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New hope for tough ovarian cancer: drug combo trial launches

NCT ID NCT05446298

First seen Apr 24, 2026 · Last updated May 24, 2026 · Updated 3 times

Summary

This study tests a combination of two drugs, ONC-392 and pembrolizumab, in 58 women with ovarian cancer that has stopped responding to platinum-based chemotherapy. The goal is to see if the combo can shrink tumors and control the disease. Participants must have a specific type of ovarian cancer and have had standard surgery.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Baptist Health Lexington, 407

    Lexington, Kentucky, 40503, United States

  • Baptist MD Anderson Cancer Center, 404

    Jacksonville, Florida, 32207, United States

  • Cancer Treatment Centers of America, Chicago. 410

    Zion, Illinois, 60099, United States

  • Cancer Treatment Centers of America, Phoenix. 403

    Goodyear, Arizona, 85338, United States

  • Center of Hope, 413

    Reno, Nevada, 89511, United States

  • Honor Health, USOR, 406

    Phoenix, Arizona, 85082, United States

  • Medical College of Wisconsin, 408

    Milwaukee, Wisconsin, 53226, United States

  • Minnesota Oncology Hematology, P. A. - USOR, 421

    Maplewood, Minnesota, 55109, United States

  • Northwest Cancer Centers - Dyer, IN - USOR, 422

    Dyer, Indiana, 46311, United States

  • Norton Cancer Institute - St. Matthews, 416

    Louisville, Kentucky, 40207, United States

  • Nuvance Health System, 401

    Danbury, Connecticut, 06856, United States

  • Oncology Associates of Oregon, P. C. - USOR. 419

    Eugene, Oregon, 97401, United States

  • Sudarshan Sharma, MD. LTD. 414

    Hinsdale, Illinois, 60521, United States

  • Texas Oncology - Northeast Texas - USOR, 423

    Tyler, Texas, 75702, United States

  • Texas Oncology, P. A. - Austin, USOR. 417

    Austin, Texas, 78731, United States

  • Texas Oncology, P. A. Woodlands - USOR, 418

    The Woodlands, Texas, 77380, United States

  • Texas Oncology, P.A., Fort Worth - USOR. 420

    Fort Worth, Texas, 76104, United States

  • The Ohio State University James Cancer Center, 412

    Columbus, Ohio, 43210, United States

  • The Valley Hosptial, Inc. 411

    Ridgewood, New Jersey, 07450, United States

  • Willis-Knighton Physician Network / Gynecologic Oncology Associates, 409

    Shreveport, Louisiana, 71103, United States

  • Women's Cancer Care Associates, LLC. 405

    Albany, New York, 12208, United States

Conditions

Explore the condition pages connected to this study.