New hope for tough ovarian cancer: drug combo trial shows promise
NCT ID NCT05446298
First seen Apr 24, 2026 · Last updated May 15, 2026 · Updated 1 time
Summary
This study tests whether a new drug (ONC-392) combined with an existing immunotherapy (pembrolizumab) can shrink tumors or slow disease in people with ovarian cancer that no longer responds to platinum chemotherapy. About 58 adults with high-grade serous ovarian, primary peritoneal, or fallopian tube cancer are taking part. The goal is to see if the combination is safe and effective at controlling the cancer.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Baptist Health Lexington, 407
Lexington, Kentucky, 40503, United States
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Baptist MD Anderson Cancer Center, 404
Jacksonville, Florida, 32207, United States
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Cancer Treatment Centers of America, Chicago. 410
Zion, Illinois, 60099, United States
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Cancer Treatment Centers of America, Phoenix. 403
Goodyear, Arizona, 85338, United States
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Center of Hope, 413
Reno, Nevada, 89511, United States
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Honor Health, USOR, 406
Phoenix, Arizona, 85082, United States
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Medical College of Wisconsin, 408
Milwaukee, Wisconsin, 53226, United States
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Minnesota Oncology Hematology, P. A. - USOR, 421
Maplewood, Minnesota, 55109, United States
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Northwest Cancer Centers - Dyer, IN - USOR, 422
Dyer, Indiana, 46311, United States
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Norton Cancer Institute - St. Matthews, 416
Louisville, Kentucky, 40207, United States
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Nuvance Health System, 401
Danbury, Connecticut, 06856, United States
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Oncology Associates of Oregon, P. C. - USOR. 419
Eugene, Oregon, 97401, United States
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Sudarshan Sharma, MD. LTD. 414
Hinsdale, Illinois, 60521, United States
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Texas Oncology - Northeast Texas - USOR, 423
Tyler, Texas, 75702, United States
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Texas Oncology, P. A. - Austin, USOR. 417
Austin, Texas, 78731, United States
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Texas Oncology, P. A. Woodlands - USOR, 418
The Woodlands, Texas, 77380, United States
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Texas Oncology, P.A., Fort Worth - USOR. 420
Fort Worth, Texas, 76104, United States
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The Ohio State University James Cancer Center, 412
Columbus, Ohio, 43210, United States
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The Valley Hosptial, Inc. 411
Ridgewood, New Jersey, 07450, United States
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Willis-Knighton Physician Network / Gynecologic Oncology Associates, 409
Shreveport, Louisiana, 71103, United States
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Women's Cancer Care Associates, LLC. 405
Albany, New York, 12208, United States
Conditions
Explore the condition pages connected to this study.