Two-Step surgery could prevent ovarian cancer without early menopause
NCT ID NCT05287451
First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 29 times
Summary
This study is for women with BRCA or other gene mutations that raise their risk of ovarian cancer. Instead of removing both ovaries and fallopian tubes at once, researchers are testing a two-step approach: remove the fallopian tubes first, then the ovaries years later. The goal is to see if this method is just as good at preventing cancer while delaying early menopause. About 100 women will take part in this US study.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Locations
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Dana Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
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Lyndon Baines Johnson General
RECRUITINGHouston, Texas, 77026, United States
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M D Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
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Mayo Clinic
RECRUITINGRochester, Minnesota, 55905, United States
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Memorial Sloan Kettering Cancer Center
RECRUITINGNew York, New York, 10065, United States
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Mount Sinai Health System
RECRUITINGNew York, New York, 10029, United States
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University of Pennsylvania
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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University of Washington
RECRUITINGSeattle, Washington, 98195, United States
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WU St Louis
RECRUITINGSt Louis, Missouri, 63130, United States
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Conditions
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