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New strategy may let BRCA carriers delay menopause while cutting cancer risk

NCT ID NCT01907789

First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 25 times

Summary

This study looks at three approaches for women with BRCA gene mutations who are at high risk for ovarian cancer: regular screening, removing both ovaries and fallopian tubes at once, or removing only the fallopian tubes first and the ovaries later. The goal is to see if delaying ovary removal helps women avoid early menopause while still lowering cancer risk. About 80 premenopausal women aged 30-47 are taking part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • NorthShore University Health System

    Evanston, Illinois, 60201, United States

  • University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.