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Sleep apnea treatment may boost brain function and Well-Being, new study hopes to show

NCT ID NCT06312956

Knowledge-focused Sponsor: Istituto Auxologico Italiano Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study follows 65 adults with obstructive sleep apnea to see how three weeks of CPAP therapy changes their thinking skills, blood markers of brain health, and emotional well-being. Participants complete memory and attention tests, give blood samples, and fill out questionnaires before and after treatment. The goal is to better understand the full benefits of CPAP beyond just improving breathing during sleep.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Continuous Positive Airway Pressure (CPAP) device
What this could lead to
If successful, this study could clarify how CPAP therapy affects thinking skills, brain health markers, and emotional well-being in people with sleep apnea.
What could go wrong
This is a small, early observational study (65 people) without a control group, so results may not apply broadly. It measures short-term changes only, not long-term outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 65 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2024

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Individual affected by OSAS

Ages

20 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * OSAS diagnosis (AHI \> 5) * handedness: right Exclusion Criteria: * previous ventilotherapy * neurological and/or neurodegenerative conditions * Personality disorders, autism spectrum disorders, schizophrenia, psychosis * sleep disorders comorbidities (eg., narcolepsy)

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Conditions

The condition(s) this trial relates to.

cognitive disorder Cognitive Dysfunction Neurologic Manifestations obstructive sleep apnea syndrome Psychological Well-Being sleep disorder sleep-wake disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cognitive change Cognitive impairment Neurologic signs Obstructive sleep apnea Sleep disorder Well-being, psychological

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • IRCCS Istituto Auxologico Italiano

    RECRUITING

    Piancavallo, VCO, 28824, Italy

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