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Sleep apnea study to reveal how CPAP alters body signals

NCT ID NCT07406620

Knowledge-focused Sponsor: King's College London Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 11, 2026 · Updated 4 times

Summary

This study looks at how continuous positive airway pressure (CPAP) therapy affects body signals like oxygen levels, heart rate, and breathing in adults with obstructive sleep apnea. Researchers will analyze data from 160 people who completed a previous trial, comparing signals before treatment and after three and six months of CPAP use. The goal is to understand how CPAP changes the complexity of these signals, which may help improve future treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 139 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2026

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

PAP-naive adults with obstructive sleep apnea (OSA), identified from the Sleep and Ventilation Service at Royal Free London NHS Foundation Trust, who participated in the 3DPiPPIn randomised controlled trial.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participation in the 3DPiPPIn trial * Availability of physiological signal data at baseline and at least one follow-up time point (i.e. three months and/or six months post-CPAP) * Provision of informed consent permitting the use of their data in future research Exclusion Criteria: * Non-participation in the 3DPiPPIn trial * Absence of physiological signal data at both follow-up time points (i.e. no available data at either three months or six months post-CPAP) * No consent for the use of their data in future research

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Conditions

The condition(s) this trial relates to.

obstructive sleep apnea syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Obstructive sleep apnoea (OSA)

Contacts and locations

Locations

  • King's College London

    London, WC2R 2LS, United Kingdom

  • Royal Free Hospital

    London, NW2 2QG, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.