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Can a brace and targeted exercises ease spondylolisthesis pain?

NCT ID NCT06989138

Disease control Sponsor: Medipol University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time

Summary

This study tests whether wearing a soft back brace for several weeks, combined with either stabilization or conventional exercises, can reduce pain, improve physical function, and boost quality of life in adults with spondylolisthesis. Participants are adults aged 18-65 with mild to moderate spondylolisthesis who do not need surgery. The trial compares the effects of the two exercise programs with the brace on pain, balance, disability, and well-being.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
A soft back orthosis (brace) combined with either stabilization or conventional exercise training
What this could lead to
If effective, this approach could offer a non-surgical way to reduce pain and improve function and quality of life for people with spondylolisthesis.
What could go wrong
This is a small, early-stage trial, and results may not apply to everyone. The brace and exercises may not outperform standard care, and some people may find the brace uncomfortable.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 48 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2025

Expected to finish

Feb 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Individuals aged 18-65 * Individuals without indication for surgery * Individuals diagnosed with grade 1-2 spondylolysis * Individuals without neurological deficits * Individuals diagnosed with radicular pain or non-specific chronic low back pain for more than 3 months Exclusion Criteria: * Surgery recommended after diagnosis * History of lumbar surgery * Presence of rheumatic inflammatory diseases or diabetic polyneuropathy * Individuals with symptoms of cauda equina or ischemic heart disease * Presence of back pain with non-mechanical causes or non-radicular neuropathic pain * Having received this type of exercise therapy before

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Conditions

The condition(s) this trial relates to.

Kinesiophobia Motor Activity spondylolisthesis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Exercise training Orthosis Spondylolisthesis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Istanbul Medipol University

    RECRUITING

    Istanbul, Istanbul, Turkey (Türkiye)

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