Probiotics in pregnancy: tiny study tracks Baby's gut bugs
NCT ID NCT06241222
First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This completed study looked at how taking probiotics during pregnancy might influence the bacteria in a newborn's gut. Researchers gave 14 pregnant women a daily probiotic tablet and compared their babies' gut bacteria to those whose mothers took no probiotics. They collected milk and stool samples for 6 months to analyze the microbial makeup. The goal was to understand where a baby's first gut bacteria come from and whether probiotics can shape them.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Probiotic blend (Bifidobacterium longum, Lactobacillus delbrueckii bulgaricus, Streptococcus thermophilus)
- What this could lead to
- If successful, this could help us understand how probiotics during pregnancy shape a baby's gut health, potentially guiding future recommendations.
- What could go wrong
- This is a very small, early study (30 participants) focused on measuring bacteria, not on health outcomes. Results may not apply to all populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
30 people
The number who actually took part.
- Started
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Jan 2018
- Finished
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Dec 2021
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 45 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Pregnant inclusive criteria were: 1. Chinese woman who is pregnant with a single fetus; 2. First pregnancy and term delivery. Newborns' inclusive criteria were: 1. Normal weight (\>2500 g, \<4000 g); 2. Term Infant (\>37 weeks, \<42 weeks). 3. Natural birth. Pregnancy exclusive criteria were: 1. Gastrointestinal disease or family history; 2. Vaginitis before pregnancy; 3. Antibiotic usage during pregnancy; 4. Hypertension, Diabetes Mellitus, Hyperthyroidism, Hypothyroidism, Autoimmune Disease, or Other Endocrine and Metabolic Disease; 5. Gestational Hypertensive Disease, Gestational Diabetes Mellitus or Other Gestational Disease; 6. Transfusion History, Organ Transplantation History or Immunotherapy History. Newborn's exclusive criteria were: 1. Abnormal weight (\>4000 g, \<2500 g); 2. With Congenital Diseases;3. Intrapartum Fetal Complication.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Zhe Li
Guangzhou, Guangdong, 510000, China
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