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Can a special cleaner cut ICU infections?

NCT ID NCT05673226

Disease control Sponsor: Hospital Israelita Albert Einstein Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested whether using a special cleaning product called organosilane, in addition to standard cleaning, could lower the number of infections patients get in intensive care units (ICUs). Over 10,000 adult patients in ICUs took part. Researchers compared infection rates when rooms were cleaned with organosilane plus traditional methods versus traditional cleaning alone.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Organosilane (a surface disinfectant)
What this could lead to
If effective, this cleaning method could help reduce the spread of infections in hospital intensive care units.
What could go wrong
This is a completed trial, but results may not apply to all hospitals or patient groups. The intervention is a cleaning product, not a treatment for existing infections.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

10,301 people

The number who actually took part.

Started

Nov 2023

Finished

Jan 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * All patients aged 18 years and older who will be admitted to the participating ICUs Exclusion Criteria: * Patients under 18 years * ICUs that may use any organosilane formulation for surface disinfection

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Conditions

The condition(s) this trial relates to.

Catheter-Related Infections Infections Pneumonia, Ventilator-Associated urinary tract infection nosocomial infection prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Infection, hospital

Contacts and locations

Locations

  • A.C. Camargo Cancer Center

    São Paulo, Brazil

  • Hospital Ana Nery

    Salvador, Brazil

  • Hospital Ernesto Dornelles

    Porto Alegre, Brazil

  • Hospital Escola Universidade Federal de Pelotas

    Pelotas, Brazil

  • Hospital Geral de Goiânia

    Goiânia, Brazil

  • Hospital Jean Bittar

    Belém, Brazil

  • Hospital Otoclínica

    Fortaleza, Brazil

  • Hospital Presidente Vargas

    São Luís, Brazil

  • Hospital Santa Cruz

    Santa Cruz do Sul, Brazil

  • Hospital Universitário de Brasília

    Brasília, Brazil

  • Hospital de Base do Distrito Federal

    Brasília, Brazil

  • Hospital do Coração

    São Paulo, Brazil

  • Hospital do Tricentenário

    Olinda, Brazil

  • Santa Casa de Misericórdia

    Belo Horizonte, Brazil

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