Can a special cleaner cut ICU infections?

NCT ID NCT05673226

Completed Disease control Sponsor: Hospital Israelita Albert Einstein Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested whether using a special cleaning product called organosilane, in addition to standard cleaning, could lower the number of infections patients get in intensive care units (ICUs). Over 10,000 adult patients in ICUs took part. Researchers compared infection rates when rooms were cleaned with organosilane plus traditional methods versus traditional cleaning alone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Organosilane (a surface disinfectant)
What this could lead to: If effective, this cleaning method could help reduce the spread of infections in hospital intensive care units.
What could go wrong: This is a completed trial, but results may not apply to all hospitals or patient groups. The intervention is a cleaning product, not a treatment for existing infections.

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Conditions

The condition(s) this trial relates to.

Catheter-Related Infections Infections Pneumonia, Ventilator-Associated urinary tract infection nosocomial infection prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INFECTION, HOSPITAL

Contacts and locations

Locations

A.C. Camargo Cancer Center

São Paulo, Brazil
Hospital Ana Nery

Salvador, Brazil
Hospital Ernesto Dornelles

Porto Alegre, Brazil
Hospital Escola Universidade Federal de Pelotas

Pelotas, Brazil
Hospital Geral de Goiânia

Goiânia, Brazil
Hospital Jean Bittar

Belém, Brazil
Hospital Otoclínica

Fortaleza, Brazil
Hospital Presidente Vargas

São Luís, Brazil
Hospital Santa Cruz

Santa Cruz do Sul, Brazil
Hospital Universitário de Brasília

Brasília, Brazil
Hospital de Base do Distrito Federal

Brasília, Brazil
Hospital do Coração

São Paulo, Brazil
Hospital do Tricentenário

Olinda, Brazil
Santa Casa de Misericórdia

Belo Horizonte, Brazil

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