New daily pill could help teens shed pounds in major trial
NCT ID NCT06672939
First seen Nov 01, 2025 · Last updated Jun 18, 2026 · Updated 39 times
Summary
This study tests a once-daily pill called orforglipron to help teenagers with obesity or overweight lose weight. About 150 teens will take either the pill or a placebo for 18 months, along with lifestyle advice. The goal is to see if the pill safely reduces body mass index (BMI) and improves quality of life.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Addenbrookes Hospital
RECRUITINGCambridge, CB2 0QQ, United Kingdom
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Alder Hey Children's Hospital
NOT_YET_RECRUITINGLiverpool, L13 0BH, United Kingdom
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Ann & Robert H. Lurie Children's Hospital of Chicago
ACTIVE_NOT_RECRUITINGChicago, Illinois, 60611, United States
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Azienda Ospedaliera Universitaria Integrata Verona - Ospedale Borgo Trento
RECRUITINGVerona, 37126, Italy
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Azienda Ospedaliero Universitaria Maggiore della Carità
RECRUITINGNovara, 28100, Italy
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Azienda Ospedaliero Universitaria Meyer
RECRUITINGFlorence, 50139, Italy
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Barnsley Hospital NHS Foundation Trust
RECRUITINGBarnsley, S75 2EP, United Kingdom
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Bristol Royal Hospital for Children
NOT_YET_RECRUITINGBristol, BS2 8BJ, United Kingdom
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Carey Chronis MD Pediatric, Infant and Adolescent Medicine
ACTIVE_NOT_RECRUITINGVentura, California, 93003-5369, United States
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Children's Healthcare of Atlanta - Center for Advanced Pediatrics
ACTIVE_NOT_RECRUITINGAtlanta, Georgia, 30329, United States
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Childrens Hospital of Pittsburgh
ACTIVE_NOT_RECRUITINGPittsburgh, Pennsylvania, 15224, United States
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Dynamed Clinical Research, LP d/b/a DM Clinical Research
ACTIVE_NOT_RECRUITINGHouston, Texas, 77065, United States
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FutureMeds - Targowek
RECRUITINGWarsaw, 03-291, Poland
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FutureMeds sp. z o. o.
ACTIVE_NOT_RECRUITINGWroclaw, 53-673, Poland
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Hull Royal Infirmary
RECRUITINGHull, HU3 2JZ, United Kingdom
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Instytut Diabetologii - Warsaw
RECRUITINGWarszewo, 2117, Poland
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Isesaki Municipal Hospital
RECRUITINGIsesaki-shi, 372-0817, Japan
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Krakowskie Centrum Medyczne - FutureMeds
RECRUITINGKrakow, 31-501, Poland
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La Providence Pediatrics Clinic - Chemidox Clinical Trials
ACTIVE_NOT_RECRUITINGHouston, Texas, 77071-1008, United States
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Lucas Research, Inc.
ACTIVE_NOT_RECRUITINGMorehead City, North Carolina, 28557, United States
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Martin Diagnostic Clinic
ACTIVE_NOT_RECRUITINGTomball, Texas, 77375-3332, United States
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MedPharmics, LLC
RECRUITINGGulfport, Mississippi, 39503-2637, United States
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Nara Prefecture General Medical Center
RECRUITINGNara, 630-8054, Japan
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Ninewells Hospital
RECRUITINGDundee, DD1 9SY, United Kingdom
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Northwick Park Hospital
RECRUITINGHarrow, HA1 3UJ, United Kingdom
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Osaka City General Hospital
RECRUITINGOsaka, 534-0021, Japan
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Sagaekiminami Clinic
RECRUITINGSaga, 840-0801, Japan
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Saitama Medical University Hospital
RECRUITINGIruma-Gun, 350-0495, Japan
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Shaare Zedek Medical Center
RECRUITINGJerusalem, 9013102, Israel
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Shamir Medical Center
RECRUITINGBeer Jacob, 73100, Israel
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Sheba Medical Center
RECRUITINGRamat Gan, 52621, Israel
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Shiga General Hospital
RECRUITINGMoriyama, 524-8524, Japan
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Shikoku Medical Center for Children and Adults
RECRUITINGZentsujichó, 765-8507, Japan
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Stamford Therapeutics Consortium
ACTIVE_NOT_RECRUITINGStamford, Connecticut, 06905, United States
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Sundance Clinical Research
ACTIVE_NOT_RECRUITINGSt Louis, Missouri, 63141-7068, United States
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Tokyo Medical Center
NOT_YET_RECRUITINGMeguro-Ku, 152-0021, Japan
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University Hospital,Kyoto Prefectural University of Medicine
NOT_YET_RECRUITINGKawaramachidori, Kamigyo-ku, Kyoto-city, 602-8566, Japan
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Vanderbilt Health One Hundred Oaks
ACTIVE_NOT_RECRUITINGNashville, Tennessee, 37212, United States
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Velocity Clinical Research
ACTIVE_NOT_RECRUITINGLafayette, Louisiana, 70508, United States
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Velocity Clinical Research, Salt Lake City
RECRUITINGSouth Jordan, Utah, 84088, United States
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.