New study aims to fix who gets left out of stroke research
NCT ID NCT06576089
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This pilot study tests better ways to recruit a wider range of people into stroke rehabilitation research, especially women and those with aphasia (trouble speaking or understanding language). Researchers will compare a new, more supportive recruitment approach to the usual method at multiple hospitals. The goal is to make sure study results reflect the real stroke population, leading to treatments that work for everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 120 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2025
- Expected to finish
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Jun 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Primary ischemic anterior circulation stroke 2. Age ≥18 years 3. ≥5 days but \<8 weeks after stroke on the date of medication (Maraviroc or placebo) start 4. Hemiparesis requiring inpatient rehabilitation 5. Assistance available for daily rehabilitation training practice and for transportation when needed 6. Adequate language skills to understand Informed Consent and retain information during daily therapies 7. At least one of the following: some shoulder abduction with gravity eliminated and visible extension in two or more digits OR visible hip flexion or extension Exclusion Criteria: 1. Pre-stroke modified Rankin score ≥2 2. Limited resources or illness that will not enable a return to living outside of a facility 3. History of dementia 4. History of hepatitis or elevated hepatic transaminases or bilirubin 5. History of renal insufficiency or creatinine clearance (eGFR) \<60mL / min / 1.73m2 6. Cancer or other chronic illness that makes 1-year survival unlikely or will detract from the ability to carry out exercise and skills practice 7. Existing pre-stroke serious disabling disease (e.g., Parkinson's disease, severe traumatic brain injury, amputation) 8. Seizure related to stroke 9. Acute or chronic epilepsy 10. Currently taking any of the following anticonvulsant medications: Carbamazepine, Phenobarbital, Phenytoin 11. Pregnant, breastfeeding, or positive test for pregnancy at baseline 12. Women of childbearing potential who are not using one highly effective form of contraception or two forms of effective contraception 13. Known HIV positivity 14. Currently taking any of the following antifungal and/or antibacterial medications: Ketoconazole, Itraconazole, Voriconazole, Rifampin, Clarithromycin, Rifabutin + Protease Inhibitor 15. Currently taking St. John's Wort
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
5 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Dalhousie University
RECRUITINGHalifax, Nova Scotia, B3H 3J5, Canada
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Parkwood Institute
RECRUITINGLondon, Ontario, N6C 0A7, Canada
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Toronto Rehabilitation Institute - University Health Network
NOT_YET_RECRUITINGToronto, Ontario, M5G 2A2, Canada
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University of British Columbia & GF Strong Rehabilitation Centre
RECRUITINGVancouver, British Columbia, V5Z 2G9, Canada
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University of Calgary & Foothills Medical Centre
RECRUITINGCalgary, Alberta, T2N 2T9, Canada
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Robot could let stroke patients rehab their hands at home without a therapist
- Moving patterns may help stroke survivors read faster
- Vibrating wearables put stroke walking to the test
- Robot plus electrical stimulation aims to rebuild arm movement after stroke
- Can a checklist and heart monitor stop repeat strokes?
- Heart hole or stroke trigger? global registry tracks who gets closure and what happens next