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Massive study tests which diabetes pill better protects heart failure patients

NCT ID NCT07390110

First seen Feb 05, 2026 · Last updated May 23, 2026 · Updated 12 times

Summary

This study compares two diabetes medications, oral semaglutide and sitagliptin, in over 25,000 adults with type 2 diabetes and a specific type of heart failure (preserved ejection fraction). The goal is to see which drug better prevents serious heart events like hospitalizations or death. Researchers are using real-world data from insurance claims and medical records to mimic a traditional clinical trial.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02120, United States

Conditions

Explore the condition pages connected to this study.