Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

New Jaw-Moving mouthpiece could ease sleep apnea without the stress

NCT ID NCT07414420

Symptom relief Sponsor: University of Belgrade Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new oral appliance called DPOA that gently and gradually moves the jaw forward during sleep to keep the airway open in people with mild to moderate obstructive sleep apnea. Forty adults aged 20 to 65 will be enrolled and monitored with sleep tests. The goal is to see if this device reduces breathing pauses and improves sleep quality better than standard appliances.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
dynamic propulsion oral appliance (DPOA)
What this could lead to
If it works, this could offer a more comfortable and effective oral appliance for people with mild to moderate sleep apnea.
What could go wrong
This is a small, early-stage trial with only 40 participants, so results may not apply to everyone. The device may not work better than existing options.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Mar 2026

An estimate. Start dates often move.

Expected to finish

Sep 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * age between 20 and 65 years * clinically confirmed diagnosis of mild or moderate obstructive sleep apnea (Apnea hypopnea index 15-30 episodes/hour) * sufficient number of periodontally healthy teeth to support the oral appliance * written informed consent of conformance with the study protocol Exclusion Criteria: * age bellow 20 and over 65 years * patients not able or not willing to follow the study protocol * patients with severe OSA (Apnea hypopnea index \> 30 episodes/hour) and/or some other breathing disturbances * patients with psychiatric, neurological or psychosomatic disorders * patients with Body Mass Index \> 29kg/sqm * pregnancy * presence of the anatomical obstruction in the airways * severe periodontal disease (III and IV grade) * pathological changes in the structures of TMJ, muscles or ligaments * mandibular protrusion less than 3mm * orthodontic anomalies, malocclusions, II and III skeletal class, and orthodontic appliances

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Obstructive sleep apnea (OSA) are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

obstructive sleep apnea syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Obstructive sleep apnea (OSA)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University of Belgrade School of Dental Medicine

    Belgrade, 11000, Serbia

More trials for these conditions

Other studies related to the condition(s) this trial covers.