Hip surgery pain relief: less may be more?
NCT ID NCT07023120
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at how much numbing medicine (ropivacaine) and whether adding dexamethasone affects pain control after hip replacement. 120 adults were split into four groups, each getting a different combination. The goal was to see which approach delays the need for strong painkillers and reduces overall opioid use.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- ropivacaine and dexamethasone
- What this could lead to
- If successful, this could lead to better pain relief and less opioid use after hip replacement surgery.
- What could go wrong
- This is a small, completed Phase 4 trial. The results may not apply to all patients or surgeries, and the best dose may still need more testing.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
-
120 people
The number who actually took part.
- Started
-
Jun 2025
- Finished
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Feb 2026
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
60 to 100 years
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged ≥18 years scheduled for primary unilateral total hip arthroplasty (THA). * American Society of Anesthesiologists (ASA) physical status I-III. * Ability to provide written informed consent. * Spinal anesthesia planned as the primary anesthetic technique. * Body mass index (BMI) between 18 and 35 kg/m². * Fluent in the local language and able to understand the NRS pain scoring system. Exclusion Criteria: * Known allergy or hypersensitivity to ropivacaine, dexamethasone, or other amide local anesthetics. * Pre-existing neurological deficits or neuropathies affecting lower limb motor or sensory function. * Chronic opioid use (daily use \>30 mg oral morphine equivalents for \>1 month prior to surgery). * History of coagulopathy, current anticoagulant therapy not eligible for regional anesthesia. * Uncontrolled diabetes mellitus (HbA1c \> 9%) or active systemic infection. * Pregnancy or breastfeeding. * Previous surgery or implantation on the ipsilateral hip. * Inability to cooperate with postoperative assessments or participate in follow-up.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Poznan University of Medical Sciences
Poznan, Poland
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Other studies related to the condition(s) this trial covers.
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