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Morning or afternoon brain games? study seeks best timing for ICU recovery

NCT ID NCT05467410

Knowledge-focused Sponsor: University of Washington Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether doing brain-training exercises in the morning or the afternoon helps older adults (60+) recover thinking skills after a stay in the intensive care unit. Forty participants will either train in the morning, in the late afternoon/evening, or receive usual care. The main goal is to see if the timing is practical and acceptable, not yet to prove it works.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
computerized cognitive training (Lumosity brain games)
What this could lead to
If successful, this could show the best time of day for brain exercises to help older ICU survivors recover thinking and sleep.
What could go wrong
This is a very small, early feasibility study with only 40 people. It is not designed to prove the training works, only whether it is possible to do.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2023

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥ 60 years * ICU length of stay ≥ 24 hours * Active transfer order or expected discharge from ICU to a post-ICU unit * Fluent in English * Functional independence prior to hospital admission (Katz Index = 6) * No suspicion of Alzheimer's disease/dementia * Current hospitalization at University of Washington Medical Center or Harborview Medical Center Exclusion Criteria: * Documented history or suspicion of Alzheimer's disease/dementia, or current prescription of anti-dementia medication * Documented history of bipolar disorder or schizophrenia * Documented acute stroke or acute traumatic brain injury * Severe visual impairment * Severe hearing impairment * Severe dominant arm paresis/paralysis * Transfer from inpatient rehabilitation or skilled nursing care facility

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Conditions

The condition(s) this trial relates to.

circadian rhythm sleep disorder Cognitive Dysfunction Critical Illness delirium

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Aging Circadian dysrhythmia Cognitive impairment Critical illness Intensive care unit delirium Older people

Contacts and locations

Locations

  • Harborview Medical Center

    Seattle, Washington, 98104, United States

  • University of Washington Medical Center

    Seattle, Washington, 98195, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.