New heart ablation method aims to boost success for persistent AF patients
NCT ID NCT04101539
First seen Nov 01, 2025 · Last updated May 21, 2026 · Updated 33 times
Summary
This study tested whether adding a personalized ablation approach called OPTIMA to the standard pulmonary vein isolation (PVI) procedure could improve outcomes for people with persistent atrial fibrillation (AF). About 67 adults with persistent AF were randomly assigned to receive either PVI alone or PVI plus OPTIMA, which uses MRI scans and computer modeling to identify specific areas in the heart that trigger AF. The goal was to see if the combined approach could increase the number of patients free from AF one year after the procedure.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Johns Hopkins Hospital
Baltimore, Maryland, 21287, United States
Conditions
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