Eye ultrasound could spot hidden artery disease
NCT ID NCT07001059
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study is testing whether measuring the optic nerve sheath with ultrasound can reliably diagnose giant cell arteritis (GCA), a condition that can cause blindness. Researchers will enroll 190 people over 50 with suspected GCA and compare ultrasound results to the final diagnosis after 6 months. If the method works, it could offer a quicker, safer way to detect the disease.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- orbital ultrasound
- What this could lead to
- If successful, this could provide a faster, non-invasive way to diagnose giant cell arteritis, potentially preventing vision loss.
- What could go wrong
- This is an early diagnostic study, not a treatment trial. The ultrasound method may not prove reliable enough to replace current diagnostic approaches.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 190 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2025
- Expected to finish
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Mar 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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50 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patient with suspected GCA * Patient over 50 years Exclusion Criteria: * Patient with history of GCA * Patient with a history of polymyalgia rheumatic (PMR) without initial PET scan * Patient with a history of retinal disease, demyelinating disease, or intracranial hypertension * Use of corticosteroids \> 0.5mg/kg in the last 2 weeks
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Get notified about this study
Sign up to get updates when this study changes or when new studies for Giant cell arteritis (GCA) are added.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
9 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Internal Medecine Department- CHU Caen
RECRUITINGCaen, France
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Internal Medicine and Clinical Immulogy department - Centre Hospitalier Universitaire de Dijon
NOT_YET_RECRUITINGDijon, France
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Internal Medicine and VascularMedecine Department - Centre Hospitalier Universitaire de Nantes
NOT_YET_RECRUITINGNantes, France
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Internal Medicine department - Hôpital Saint-Antoine
NOT_YET_RECRUITINGParis, France
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Rhumatology departement - Centre Hospitalier Aix en Provence
NOT_YET_RECRUITINGAix-en-Provence, France
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Rhumatology department - Centre Hospitalier Universitaire de Brest
NOT_YET_RECRUITINGBrest, France
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Rhumatology department - Centre Hospitalier Universitaire de Tours
NOT_YET_RECRUITINGTours, France
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Rhumatology department - Hôpital Bichat
NOT_YET_RECRUITINGParis, France
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Rhumatology department - Hôpital NOVO - Pontoise site
NOT_YET_RECRUITINGPontoise, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can frequent CRP checks prevent relapses in giant cell arteritis?
- Ultrasound clue vanishes days after steroids start in artery disease
- New Total-Body PET scanner could revolutionize vasculitis diagnosis
- New drug combo aims to tame blood vessel inflammation
- Could 8 weeks of steroids be enough? new trial aims to cut treatment time for GCA
- New ultrasound method could predict relapses in rare artery disease