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Can simple habits help you keep weight off? new study tests best combinations

NCT ID NCT06785064

Disease control Sponsor: University of Alabama at Birmingham Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study aims to find the best combination of strategies to help people maintain weight loss after losing at least 5% of their body weight. Over 500 participants will first lose weight through a 16-week program, then be assigned to different packages of four methods: eating fewer high-calorie foods, home strength training, buddy support, and workshops to handle tough thoughts. Researchers will compare 16 different packages over 12 months to see which works best.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Reduced Food Variety, Home-based Resistance Training, Buddy Training and Support, Acceptance and Commitment Workshops
What this could lead to
If successful, this could identify the best combination of low-cost strategies to help people maintain weight loss long-term.
What could go wrong
This is a behavioral study, not a drug trial, so results may vary by individual. The strategies may not work for everyone, and long-term adherence could be challenging.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 544 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2025

Expected to finish

Feb 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age \>18 years * Body mass index (BMI) \>30 kg/m2 * Has regular access to internet (to access Zoom videoconferencing platform) * If indicated during screening, willing to obtain medical clearance for exercise from their healthcare provider prior to enrollment Exclusion Criteria: * Current or recent (past 6 months) use of prescription weight loss medications * Weight loss \>10 pounds in past 6 months (other than postpartum) * Pregnancy or anticipating pregnancy * Another household member already participating in the study * Participation in another randomized research project * Uncontrolled hypertension (blood pressure \>160/100 mm Hg at screening) * Any of the following other medical conditions: myocardial infarction or cerebrovascular accident within the last 6 months; unstable angina within the past 6 months; NYHA Class III or IV congestive heart failure; type 1 diabetes; and chronic lung diseases that limit physical activity * Unable to identify potential buddy (i.e., adult friend or family member) for extended care intervention phase * Residing \>50 miles from the university (to attend assessment visits) * Planning to relocate out of the area in the next 18 months * Does not have internet access * Unwilling or unable to do any of the following: give informed consent; read/understand English; accept random assignment

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Conditions

The condition(s) this trial relates to.

Body Weight Changes Health Behavior obesity disorder Weight Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Obesity prevention Weight change Weight loss Weight loss maintenance

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University of Alabama at Birmingham

    RECRUITING

    Birmingham, Alabama, 35205, United States

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