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Opioid vaccine trial aims to block drug high and curb relapse

NCT ID NCT04458545

First seen Apr 30, 2026 · Last updated Apr 30, 2026

Summary

This study tests a vaccine designed to help people with opioid use disorder by training the body to produce antibodies that bind to oxycodone in the blood, reducing its ability to reach the brain and cause a high. The trial involves 45 adults aged 18 to 59 and will check for safety, immune response, and whether the vaccine reduces drug liking. This approach is not a cure but aims to support long-term recovery alongside other treatments.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Clinilabs Drug Development Corporation

    RECRUITING

    Eatontown, New Jersey, 07724, United States

    Contact Phone: •••-•••-••••

  • New York State Psychiatric Institute: Division on Substance Use Disorders

    ACTIVE_NOT_RECRUITING

    New York, New York, 10032, United States

Conditions

Explore the condition pages connected to this study.