New study tests nerve block to cut opioid use in hysterectomy recovery
NCT ID NCT07178262
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests whether a nerve block called an erector spinae plane (ESP) block can reduce the need for strong painkillers (opioids) during and after a hysterectomy. Sixty women having elective hysterectomy will be randomly assigned to receive either the ESP block with bupivacaine or a placebo injection. The main goal is to see if the block lowers the amount of fentanyl needed during surgery and tramadol afterward, while also improving pain scores.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Bupivacaine (Marcaine) nerve block
- What this could lead to
- If it works, this could offer a way to manage post-surgery pain with fewer opioids, reducing side effects and addiction risk.
- What could go wrong
- This is a small, early-phase trial. The nerve block may not significantly reduce opioid use, and results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2025
- Expected to finish
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Oct 2025
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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16 to 80 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * American Society of Anesthesiologists (ASA) class: I, II and III . * Elective Hysterectomy under General Anesthesia. Exclusion Criteria: * Lack of consent * Body mass index \>35 kg/m2 * Allergic to study medicine * Opioid abuse or misuse disorder * Chronic pain
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Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Kulsoom Internation Hospital
RECRUITINGIslamabad, Federal, 44000, Pakistan
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