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Native-Focused program aims to curb opioid use in young adults

NCT ID NCT04617938

Prevention Sponsor: RAND Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jul 07, 2026 · Updated 2 times

Summary

This study tested a program called TACUNA plus Wellness Circle, designed to prevent opioid misuse among American Indian and Alaska Native young adults aged 18-25 in California. The program uses motivational interviewing and traditional practices in virtual workshops. Researchers compared it to a standard opioid education workshop over 12 months to see if it reduces drug use and strengthens healthy social networks.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
TACUNA plus Wellness Circle (behavioral intervention)
What this could lead to
If it works, this could provide a culturally tailored way to prevent opioid misuse and reduce substance use among urban AI/AN young adults.
What could go wrong
This is a completed study with 541 participants, but results are not yet widely confirmed. The intervention is behavioral, so effects may vary by individual and setting.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

541 people

The number who actually took part.

Started

Nov 2020

Finished

Jul 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 25 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * must self-identify as American Indian/Alaska Native (AI/AN) * be in the age range of 18-25 * not be in need of substance treatment Exclusion Criteria: * If substance treatment need is indicated

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Conditions

The condition(s) this trial relates to.

Alcohol Drinking Marijuana Use opioid abuse opiate dependence prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alcohol drinking Marijuana use Opioid use

Contacts and locations

Locations

  • RAND Corporation

    Santa Monica, California, 90401, United States

  • UCLA

    Los Angeles, California, 90095, United States

  • United American Indian Involvement, Inc

    Los Angeles, California, 90017, United States

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