Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Opioid-Free anesthesia: a safer way to wake up after Weight-Loss surgery?

NCT ID NCT07337135

Symptom relief Sponsor: Hospital dos Lusíadas Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether avoiding opioids during weight-loss surgery leads to less pain and fewer side effects like nausea. Sixty adults having laparoscopic bariatric surgery were randomly assigned to receive either opioid-free anesthesia (using other drugs) or standard opioid-based anesthesia. Researchers measured pain scores, need for extra painkillers, and nausea after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Opioid-free anesthesia (dexmedetomidine, ketamine, lidocaine) vs opioid-based anesthesia (remifentanil)
What this could lead to
If successful, this could show that avoiding opioids during weight-loss surgery reduces side effects like nausea and speeds recovery.
What could go wrong
This is a small, single-center trial with only 60 patients, so results may not apply broadly. The opioid-free approach may not control pain as well for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

Oct 2023

Finished

Apr 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥ 18 years; * Body mass index (BMI ≥ 35 kg/m² with associated comorbidities) or BMI ≥ 40 kg/m²; * Scheduled for elective laparoscopic bariatric surgery; * Ability to provide informed consent. Exclusion Criteria: * Pregnancy; * History of substance abuse; * Severe psychiatric disease; * Contraindications to any of the drugs used in either anesthetic protocol (dexmedetomidine, ketamine, lidocaine, remifentanil, etc.); * Inability to comply with study procedures; * Refusal or inability to provide informed consent.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Bariatric surgery are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

morbid obesity Nausea Pain, Postoperative Vomiting

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bariatric surgery Morbid obesity Opioid-free anesthesia Postoperative pain

Contacts and locations

Locations

  • Hospital Lusíadas Amadora - Lusíadas Saúde, S.A.

    Amadora, 2724-002, Portugal

More trials for these conditions

Other studies related to the condition(s) this trial covers.