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New anesthesia approach aims to reduce opioid use in nasal surgeries

NCT ID NCT07350668

Symptom relief Sponsor: Benha University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether using a combination of dexmedetomidine and lignocaine (opioid-free anesthesia) could control pain as well as standard fentanyl (opioid-based anesthesia) in 60 adults undergoing nasal surgeries like sinus surgery or septoplasty. The goal was to see if the opioid-free method reduces side effects like nausea and vomiting while still keeping patients comfortable during and after surgery. Results will help doctors choose safer anesthesia options.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

60 people

The number who actually took part.

Started

Jan 2025

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients between the ages of 18 and 60, scheduled to undergo elective nasal surgeries. * ASA (American Society of Anesthesiologists) physical status I-II. * Patients who provide written informed consent to participate in the study. Exclusion Criteria: * ASA III or above. * Patients with a history of opioid dependence or chronic pain conditions requiring long-term opioid therapy. * Patients with multiorgan failure, unstable hemodynamics prior to surgery, or scheduled for emergency surgery. * Pregnant or lactating women. * Patients with a history of severe asthma or those taking preoperative alpha-blockers.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Postoperative pain

Contacts and locations

Locations

  • Benha University Hospital

    Banhā, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.