No-Opioid anesthesia may improve recovery after gallbladder surgery
NCT ID NCT06343753
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 50 adults having planned gallbladder removal surgery. It compared two types of pain control during anesthesia: one using opioids and one without opioids. The goal was to see which approach leads to better recovery and less pain in the first 24 hours after surgery.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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50 people
The number who actually took part.
- Started
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May 2024
- Finished
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Sep 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria : * Age group: 18-65 year of both sex. * Patients with ASA (American society of anesthesiologist) classification I-II. * Undergoing a scheduled laparoscopic cholecystectomy Exclusion Criteria: * Pregnant or breast-feeding women * ASA physical status class \> 2 * The need to change laparoscopic surgery to an open one * Allergy to any of the drugs used in the study * local skin infection at the trocar injection site * 1st or 2nd degree Heart block * Chronic treatment by beta-blockers * HR \<50 bpm * Epilepsy or seizures * Alcohol or drug abuse * Psychiatric disease * History of chronic pain
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Ain Shams University
Cairo, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a nociception monitor cut opioid use in Day-Surgery gallbladder removal?