Heart surgery without morphine: safer recovery?

NCT ID NCT04940689

Completed Symptom relief Sponsor: University Hospital, Rouen Source: ClinicalTrials.gov ↗

First seen Apr 03, 2026 · Last updated May 25, 2026 · Updated 6 times

Summary

This study looked at whether avoiding morphine during heart surgery can lower the risk of serious side effects like breathing trouble, confusion, and bowel problems. 268 adults having planned heart surgery took part. Instead of morphine, doctors used a mix of other pain medicines (dexmedetomidine, ketamine, lidocaine) to keep patients comfortable. The goal was to see if this approach leads to fewer complications in the first 48 hours after surgery.

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Contacts and locations

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Locations

Amiens Univesrity Hospital

Amiens, France
CAEN university Hospital

Caen, France
Lille Hopistal University

Lille, France
Montpellier University Hospital

Montpellier, France
Rouen University Hospital

Rouen, France, Normandy, 76031, France

Conditions

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ANESTHESIA