New radiation approach aims to cut side effects for breast cancer patients
NCT ID NCT03077841
First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 34 times
Summary
This study tests a type of radiation called hypofractionated partial breast irradiation for women with early-stage breast cancer. Instead of treating the whole breast, it targets only the area where the cancer was removed, using higher doses over fewer sessions. The goal is to see if this approach causes fewer side effects while still preventing cancer from coming back. The trial includes about 928 participants who have had breast-conserving surgery.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Baptist MD Anderson Cancer Center
Jacksonville, Florida, 32207, United States
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Community Cancer Center East
Indianapolis, Indiana, 46219, United States
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Cooper Hospital University Medical Center
Camden, New Jersey, 08103, United States
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Covenant Medical Center Harrison
Saginaw, Michigan, 48602, United States
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M D Anderson Cancer Center
Houston, Texas, 77030, United States
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MD Anderson Cancer Center at Cooper-Voorhees
Voorhees Township, New Jersey, 08043, United States
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MD Anderson League City
League City, Texas, 77573, United States
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MD Anderson West Houston
Houston, Texas, 77079, United States
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MD Anderson in Sugar Land
Sugar Land, Texas, 77478, United States
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MD Anderson in The Woodlands
Conroe, Texas, 77384, United States
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OhioHealth Mansfield Hospital
Mansfield, Ohio, 44903, United States
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Piedmont Hospital
Atlanta, Georgia, 30309, United States
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Presbyterian Hospital
Albuquerque, New Mexico, 87106, United States
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Saint Luke's Baptist Health System
San Antonio, Texas, 78229, United States
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Summit Medical Group
Berkeley Heights, New Jersey, 07922, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
hypofractionated partial breast irradiation (radiation therapy)
What this could lead to
If successful, this could offer a more convenient and less toxic radiation option for early-stage breast cancer patients, potentially becoming a new standard of care.
What could go wrong
The trial is currently suspended, and it is a phase II/III study, so results are not yet confirmed. The approach may not be as effective or safe as standard whole-breast radiation for all patients.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.