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New hope for tough lung cancer: drug targets Cancer's repair system

NCT ID NCT05450965

First seen Jan 05, 2026 · Last updated May 19, 2026 · Updated 16 times

Summary

This study tests a drug called onvansertib in about 37 people with small cell lung cancer that did not respond to or could not tolerate chemotherapy. Onvansertib blocks a protein that cancer cells need to repair themselves, aiming to shrink tumors. The main goal is to see how many patients have their tumors shrink or disappear.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UPMC Hillman Cancer Center

    ACTIVE_NOT_RECRUITING

    Pittsburgh, Pennsylvania, 15232, United States

  • University of Maryland Greenebaum Comprehensive Cancer Center

    RECRUITING

    Baltimore, Maryland, 21201, United States

    Contact

    Contact

Conditions

Explore the condition pages connected to this study.