New hope for rare aggressive blood cancer: experimental drug enters human trial
NCT ID NCT06936943
First seen Nov 01, 2025 · Last updated May 21, 2026 · Updated 22 times
Summary
This study tests an experimental drug called ONO-4538 in 14 people with Richter's transformation, a rare and aggressive blood cancer that can develop from chronic lymphocytic leukemia. The main goal is to see how many patients' tumors shrink or disappear after treatment. Researchers will also track survival, side effects, and how long any benefits last.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Aichi Cancer Center
RECRUITINGNagoya, Aichi-ken, Japan
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Hiroshima Red Cross Hospital & Atomic-bomb Survivors Hospital
RECRUITINGHiroshima, Hiroshima, Japan
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Hokkaido University Hospital
RECRUITINGSapporo, Hokkaido, 060-8648, Japan
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Kindai University Hospital
RECRUITINGŌsaka-sayama, Osaka, Japan
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Kyoto University Hospital
RECRUITINGKyoto, Kyoto, Japan
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Kyusyu University Hospital
RECRUITINGFukuoka, Fukuoka, 812-8582, Japan
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National Cancer Center Hospital
RECRUITINGChuo Ku, Tokyo, Japan
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Niigata University Medical & Dental Hospital
RECRUITINGNiigata, Niigata, Japan
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Tohoku University Hospital
RECRUITINGSendai, Miyagi, Japan
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Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital
RECRUITINGBunkyō-Ku, Tokyo, Japan
Conditions
Explore the condition pages connected to this study.