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New hope for depression? experimental drug ONO-1110 enters Mid-Stage trial

NCT ID NCT06792136

Ongoing Symptom relief Sponsor: Ono Pharmaceutical Co., Ltd. Source: ClinicalTrials.gov ↗

First seen Nov 19, 2025 · Last updated May 25, 2026 · Updated 20 times

Summary

This study tests a new medicine called ONO-1110 in 100 people with major depressive disorder. Half will get the drug, half a placebo, to see if it safely reduces depression symptoms over 8 weeks. The goal is to find better treatment options for those struggling with depression.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • AK Clinic

    Fukuoka, Japan

  • Harai Clinic

    Tokyo, Japan

  • Higashi-Sapporo Mental Clinic

    Hokkaido, Japan

  • Hiro Mental Clinic

    Fukuoka, Japan

  • Hirota Clinic

    Fukuoka, Japan

  • Ichikawa Clinic

    Gunma, Japan

  • Iidabashi Mental Clinic

    Tokyo, Japan

  • Ikebukuro Olive Mental Clinic

    Tokyo, Japan

  • Kawamura Mental Clinic

    Hokkaido, Japan

  • Kishiro Mental Clinic

    Kanagawa, Japan

  • Kitaikebukuro Kokoro No Clinic

    Tokyo, Japan

  • Kokorono Clinic Hirao

    Fukuoka, Japan

  • Kokorono Clinic Iizuka

    Fukuoka, Japan

  • Kokura Mental Clinic

    Fukuoka, Japan

  • Maynds Tower Mental Clinic

    Tokyo, Japan

  • Meguroeki Higashiguchi Mental Clinic

    Tokyo, Japan

  • Mental Clinic Sakurazaka

    Fukuoka, Japan

  • Minami1jo Mental Clinic

    Hokkaido, Japan

  • Monzen-nakacho Mental Clinic

    Tokyo, Japan

  • Niseikai Murakami Iin

    Tokyo, Japan

  • Nishi-Shinjuku Concieria Clinic

    Tokyo, Japan

  • Sakurazaka Clinic SophyAnce

    Tokyo, Japan

  • Sangenjaya Nakamura Mental Clinic

    Tokyo, Japan

  • Sapporo Kobushi Clinic

    Hokkaido, Japan

  • Shimode Mental Clinic

    Hokkaido, Japan

  • Shinseikai Kaku Mental Clinic

    Fukuoka, Japan

  • Tatsuta Clinic

    Hyōgo, Japan

  • Uematsu Mental Clinic

    Fukuoka, Japan

  • Yutaka Clinic

    Kanagawa, Japan

Conditions

Explore the condition pages connected to this study.

MAJOR DEPRESSIVE DISORDER (MDD)