Daily custom radiation plans could cut breast cancer treatment delays
NCT ID NCT05727553
First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time
Summary
This trial tests a new way to deliver radiation after breast cancer surgery. Instead of using a single treatment plan for the whole course, the Ethos system creates a new plan each day based on the patient's current anatomy. The goal is to avoid delays caused by changes in breast shape or swelling. Researchers will measure how long each session takes, how patients feel about the process, and whether the daily plans improve radiation accuracy.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- online adaptive radiotherapy delivered on the Ethos system
- What this could lead to
- If successful, this approach could make breast cancer radiotherapy faster and more precise, reducing the need for treatment breaks and re-planning.
- What could go wrong
- This is a small, early-stage study focused on workflow and patient experience, not on long-term cancer outcomes. The technology may not improve results for all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
50 people
The number who actually took part.
- Started
-
Dec 2021
- Finished
-
Dec 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Breast cancer patients undergoing postoperative radiation treatment.
- Ages
-
18 years and older
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Breast cancer patients referred for postoperative radiotherapy of the breast, chest wall, axillary levels, tumor bed boost or partial breast irradiation. * Age of 18 years and older. * Adequate understanding and communicating the Dutch language. * Written informed consent for use of routinely collected clinical data and to fill out questionnaires. Exclusion Criteria: * Patients not suitable for postoperative radiotherapy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Amsterdam UMC
Amsterdam, North Holland, 1081 HV, Netherlands
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