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Could a single daily dose beat infection around the lungs?

NCT ID NCT07095361

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 31 times

Summary

This study tests whether giving enzyme medications once a day through a chest tube works as well as the standard twice-a-day schedule for treating serious lung infections (pleural infections). About 270 adults hospitalized with infected fluid around the lung will be randomly assigned to receive either once-daily or twice-daily treatment. The goal is to see if the simpler schedule can reduce the need for surgery and improve recovery without increasing risks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Dartmouth Hitchcock Medical Center

    RECRUITING

    Lebanon, New Hampshire, 03766, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

  • Henry Ford Hospital

    RECRUITING

    Detroit, Michigan, 48202, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

  • Northwestern University

    RECRUITING

    Chicago, Illinois, 60611, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

  • Rush University Medical Center

    RECRUITING

    Chicago, Illinois, 60612, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

  • UNC Chapel Hill

    RECRUITING

    Chapel Hill, North Carolina, 27514, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Yale New Haven Hospital

    RECRUITING

    New Haven, Connecticut, 06510, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

Conditions

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