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Heart safety check for new drug in healthy volunteers

NCT ID NCT06411860

First seen Nov 01, 2025 · Last updated May 17, 2026 · Updated 30 times

Summary

This completed Phase 1 study checked whether olpasiran, an experimental drug, changes heart rhythm in 32 healthy adults aged 18 to 60. Participants received a single dose of olpasiran, a placebo, or a positive control in a crossover design. The main goal was to measure any effects on the heart's electrical activity (QT interval). The study provides safety data for future development.

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Contacts and locations

Locations

  • Fortrea Clinical Research Unit Limited - Leeds

    Leeds, LS11 9EH, United Kingdom

Conditions

Explore the condition pages connected to this study.