Can a phone app beat the gold standard for weight loss?
NCT ID NCT04708769
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a smartphone-based weight loss program (EVO) against the standard Diabetes Prevention Program (DPP) in 524 adults with obesity. Participants use an app to track diet, activity, and weight, with remote coaching. The goal is to see which approach leads to more weight loss and is more cost-effective.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- behavioral weight loss intervention via smartphone app
- What this could lead to
- If successful, this could offer a more accessible and cost-effective way to manage obesity without in-person visits.
- What could go wrong
- This is a behavioral intervention, not a drug, so results depend on participant adherence. The study is not yet complete, and the app may not work for everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 524 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2021
- Expected to finish
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Jul 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * BMI 30-45 * Weight stable * Own a Smartphone and be willing to install our Smartphone app * Willing to conduct video conference calls with study staff Exclusion Criteria: * Enrolled in any formal weight loss program * Taking anti-obesity medications * Not taking medications that may cause weight gain * Unstable medical conditions * Diabetes requiring insulin supplementation * Crohn's Disease * Diagnosis of obstructive sleep apnea requiring intervention (i.e., CPAP) * Assistive devices for mobility * Hospitalizations for a psychiatric disorder within the past 5 years * Cardiovascular disease symptoms while performing moderate intensity exercise * Pregnancy, trying to get pregnant, or lactating. * Bulimia or binge eating disorder * Reports of active suicidal ideation * Current substance abuse or dependence besides nicotine dependence
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Northwestern University
Chicago, Illinois, 60611, United States
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