Gut check: can fermentation unlock Obesity's secrets?
NCT ID NCT06768827
First seen Oct 01, 2025 · Last updated Jun 23, 2026 · Updated 27 times
Summary
This study looks at how the gut's natural fermentation process affects metabolism in young people aged 15 to 22 with obesity. Researchers will give lactulose to trigger fermentation and measure changes in fat breakdown and sugar production. The goal is to understand why some develop insulin resistance while others do not, which could lead to better treatments down the road.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Yale University
RECRUITINGNew Haven, Connecticut, 06520, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Lactulose
What this could lead to
If successful, this could reveal new ways to target insulin resistance in young people with obesity.
What could go wrong
This is an early observational study with only 55 participants, so results may not apply broadly. It does not test a treatment.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.