Hormone clues to obesity: study compares Men's body chemistry
NCT ID NCT03157778
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study measured levels of a hormone called pregnenolone and related compounds in the blood of 25 men—some with obesity and some at a healthy weight. Researchers wanted to see if a breakdown in the body's natural feedback loop might lead to overactivity of the endocannabinoid system, which is linked to obesity. The study did not test any treatment; it simply observed differences between the two groups.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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25 people
The number who actually took part.
- Started
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May 2017
- Finished
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Nov 2017
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Male participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Obese subjects: * men, * aged between 18 and 65 years, * BMI\>30kg/m2. * Normal-weight subjects: * men, * aged between 18 and 65 years, * BMI\<25kg/m2. Exclusion Criteria: * For all subjects: * cannabis detected by urinary tetrahydrocannabinol presence, * treatment which can interfere with endocannabinoid system (antidepressant, antipsychotics, anxiolytics).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hôpital Haut-Lévêque
Pessac, 33600, France
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