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New injection aims to smooth neck bands in phase 3 trial

NCT ID NCT07210463

First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 31 times

Summary

This phase 3 study tests whether NT 201 (incobotulinumtoxinA, a type of botulinum toxin) can safely reduce the appearance of moderate to severe neck bands (platysma prominence) compared to a placebo. About 300 adults in Europe will receive injections and be followed for several weeks. The main goal is to see if the bands improve by at least two grades on a five-point scale, as judged by both the doctor and the participant.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Merz Investigative Site

    RECRUITING

    Lyon, 69006, France

  • Merz Investigative Site

    RECRUITING

    Munich, Bavaria, 80539, Germany

  • Merz Investigative Site

    RECRUITING

    Blankenfelde-Mahlow, Brandenburg, 15831, Germany

  • Merz Investigative Site

    RECRUITING

    Potsdam, Brandenburg, 14467, Germany

  • Merz Investigative Site

    RECRUITING

    Friedrichsdorf, Hesse, 61381, Germany

  • Merz Investigative Site

    RECRUITING

    Kassel, Hesse, 34117, Germany

  • Merz Investigative Site

    RECRUITING

    Bochum, North Rhine-Westphalia, 44793, Germany

  • Merz Investigative Site

    RECRUITING

    Düsseldorf, North Rhine-Westphalia, 40212, Germany

  • Merz Investigative Site

    RECRUITING

    Drensteinfurt, 48317, Germany

  • Merz Investigative Site

    RECRUITING

    Hamburg, 20146, Germany

  • Merz Investigative Site

    RECRUITING

    Hamburg, 29354, Germany

  • Merz Investigative Site

    RECRUITING

    Wuppertal, 42287, Germany

  • Merz Investigative Site

    RECRUITING

    Krakow, Lesser Poland Voivodeship, 30-002, Poland

  • Merz Investigative Site

    RECRUITING

    Oświęcim, Lesser Poland Voivodeship, 32-600, Poland

  • Merz Investigative Site

    RECRUITING

    Lublin, Lublin Voivodeship, 20-607, Poland

  • Merz Investigative Site

    RECRUITING

    Warsaw, Masovian Voivodeship, 00-716, Poland

  • Merz Investigative Site

    RECRUITING

    Warsaw, Masovian Voivodeship, 01-142, Poland

  • Merz Investigative Site

    RECRUITING

    Warsaw, Masovian Voivodeship, 02-482, Poland

  • Merz Investigative Site

    RECRUITING

    Warsaw, Masovian Voivodeship, 02-953, Poland

  • Merz Investigative Site

    RECRUITING

    Bialystok, Podlaskie Voivodeship, 15-453, Poland

  • Merz Investigative Site

    RECRUITING

    Gdynia, Pomeranian Voivodeship, 81-537, Poland

  • Merz Investigative Site

    RECRUITING

    Warsaw, 02-962, Poland

  • Merz Investigative Site

    RECRUITING

    Lodz, Łódź Voivodeship, 90-436, Poland

  • Merz Investigative Site

    RECRUITING

    Ostrowiec Świętokrzyski, Świętokrzyskie Voivodeship, 27-400, Poland

  • Merz Investigative Site

    RECRUITING

    Pamplona, Navarre, 31008, Spain

  • Merz Investigative Site

    RECRUITING

    Valencia, 46010, Spain

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

IncobotulinumtoxinA (a type of botulinum toxin, also known as Xeomin or Bocouture)

What this could lead to

If it works, this could provide a safe and effective treatment to reduce the appearance of prominent neck bands, improving cosmetic concerns.

What could go wrong

This is a cosmetic treatment, not a cure for any disease. Results may vary, and there are risks like allergic reactions or temporary muscle weakness. The trial is still recruiting, so outcomes are not yet known.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.