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Can a simple supplement improve sleep for the restless?

NCT ID NCT07485959

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a dietary supplement called NP-2006 in 48 healthy adults who had mild, ongoing sleep troubles (subclinical insomnia). Participants took either the supplement or a placebo pill daily before bed for 4 weeks. Researchers measured sleep quality and daytime sleepiness using questionnaires and a wrist monitor to see if the supplement helped improve sleep efficiency.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
NP-2006 (dietary supplement)
What this could lead to
If it works, this could offer a natural option for people with mild sleep problems to get better rest without prescription drugs.
What could go wrong
This is a small, early-stage trial with only 48 people. The supplement may not work better than a placebo, and results may not apply to everyone with insomnia.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

48 people

The number who actually took part.

Started

May 2023

Finished

Aug 2025

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

19 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Those who agreed to participate in this study and signed a written consent form 2. Adults aged 19 to 65 years, male or female 3. Those with poor sleep quality (PSQI score \> 5 points) Exclusion Criteria: 1. Those with severe sleep disturbances (ISI ≥ 22 points) 2. Those with severe daytime sleepiness (ESS ≥ 16 points) 3. Those with the following conditions: * Snoring, sleep apnea, restless legs syndrome, periodic limb movement disorder (PLMD), depression, narcolepsy, or respiratory disease that cause sleep disturbances * Itching, nocturia, chronic pain, or muscle cramps that affect sleep * Uncontrolled diabetes or hypertension 4. Those experiencing changes that could cause excessive stress within 2 weeks of the first visit: death of a spouse, family discord, lawsuits/disputes, sudden financial difficulties, immigration, etc. 5. Those taking medications (corticosteroids, psychotropic medications, etc.) that could affect sleep within 1 month of the first visit or expected to take them during the study participation 6. Those receiving hormone therapy 7. Those who regularly consume excessive alcohol * Men \> 210 g/week (approximately 4 bottles of soju/week, approximately 4 glasses/day) * Women \> 140 g/week (approximately 2.5 bottles of soju/week, approximately 2.5 glasses/day) 8. Those who smoke excessively (\> 10 cigarettes/day) or show withdrawal symptoms 9. Those who consume excessive amounts of caffeine (\> 3 cups/day) 10. Those who work night shifts or have irregular bedtimes due to their job 11. Those who have traveled or plan to travel long distances to a country with a different time zone within 1 month of the first visit 12. Those with a BMI of 18 kg/m2 or less or 35 kg/m2 or more 13. Those who have continuously taken herbal medicines or health functional foods that may affect sleep within 1 month of the first visit 14. Those who are hypersensitive to ingredients in the test or control foods or have experienced severe food allergies 15. Those who have participated in a clinical trial within 1 month of the first visit 16. Those who are pregnant or lactating, or who are planning to become pregnant 17. Those who the researcher deems unsuitable for participation in this study

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Seoul National University Bundang Hospital

    Seongnam-si, Gyeonggi-do, 13620, South Korea

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