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Can prism training and electrical stimulation help stroke survivors see and walk better?

NCT ID NCT06053320

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether combining prism adaptation training with electrical stimulation can help people who have had a stroke and have spatial neglect (trouble noticing things on one side). Researchers will measure changes in pointing behavior, brain activity, and walking ability. The study includes 65 participants: healthy young adults, healthy older adults, and stroke survivors.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 65 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2023

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 90 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Young Adults Able Bodied (YAB) Individuals * 18-30 years * Able-Bodied (healthy without any physical disability or neurological disorder) Older Adults Able-Bodied Individuals (OAB) * 45-90 years * Able-Bodied (healthy without any physical disability or neurological disorder) Individuals with right hemisphere stroke (40-90 years) * \>3 months following stroke. * Presence of Aiming SN * Ability to walk \>10m with or without assistive devices. * Unilateral left-sided hemiparesis with gross arm strength of ≤ grade 4/5 on the Medical Research Council Scale * Ability to follow 3-stage commands and provide informed consent. Exclusion Criteria: Young Adults Able-Bodied (YAB) Individuals and Older Adults Able-Bodied Individuals (OAB) * History or evidence of orthopedic or physical disability * History or evidence of neurological pathology * Pregnancy (female) * Uncontrolled hypertension * Cardiac pacemaker or other implanted electronic system * Presence of skin conditions preventing the electrical stimulation setup * Impaired sensation in the left upper limb. * Bruises or cuts at the stimulation electrode placement site * Concurrent enrollment in rehabilitation or another investigational study. * History or evidence of orthopedic or physical disability interfering with study procedures * History or evidence of neurological pathology or disorder * Severe uncontrolled medical problems (e.g., hypertension, cardiovascular disease, rheumatoid arthritis, active cancer or renal disease, epilepsy) that may interfere with study procedures * Contraindications to TMS, such as metal implants, medications that can increase cortical excitability, and unexplained dizziness in the past 6 months Individuals with right hemisphere stroke (40-90 years) * History or brainstem strokes * Cerebellar disorders * Impaired sensation in the left upper limb. * History of other neurological disorders * Uncontrolled hypertension * Cardiac pacemaker or other implanted electronic system * Pregnancy (female) * Presence of skin condition * Bruises at the electrode placement site * Severe uncontrolled medical problems (e.g., hypertension, cardiovascular disease, rheumatoid arthritis, active cancer or renal disease, epilepsy) or other medical conditions that can interfere with study procedures * Contraindications to TMS, such as metal implants in the brain, medications that will increase cortical excitability, etc.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    3 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Emory Rehabilitation Hospital

    RECRUITING

    Atlanta, Georgia, 30322, United States

  • Emory University Hospital (EUH)

    RECRUITING

    Atlanta, Georgia, 30322, United States

  • Executive Park

    RECRUITING

    Atlanta, Georgia, 30329, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.