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New cream could soothe eczema and psoriasis itch

NCT ID NCT07183423

Symptom relief Sponsor: Makati Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests a new cream made with ceramide, coconut oil, and cholesterol to see if it improves skin hydration, redness, and itch in people with mild skin barrier problems like eczema, psoriasis, or dry skin. 26 adults will apply either the new cream or plain petrolatum twice daily for 28 days. Researchers will measure skin moisture, oil, and redness at weekly checkups.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Novel barrier repair cream (ceramide, virgin coconut oil, cholesterol)
What this could lead to
If it works, this could offer a new option for managing dry, itchy skin conditions like eczema and psoriasis.
What could go wrong
This is a very small pilot study with only 26 people, so results may not apply to everyone. It's too early to know if the new cream is better than standard petrolatum.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 26 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2025

Expected to finish

Oct 2025

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Clinical diagnosis of mild skin barrier dysfunction, including: * Mild to moderate atopic dermatitis, defined as SCORAD ≤ 50, and/or not currently requiring topical corticosteroids or immunomodulators. * Mild to moderate chronic plaque psoriasis, defined as total body surface area (BSA) involved: ≤3% to 10%. * Contact dermatitis * Seasonal xerosis or clinically evident skin dryness * Symmetrical or bilateral test areas available (volar forearm) * Willing and able to provide informed consent and adhere to study procedures Exclusion Criteria: * Failure to meet any of the above inclusion criteria * Severe atopic dermatitis or psoriasis requiring systemic or high-potency topical treatment * Use of corticosteroids, calcineurin inhibitors, biologics, or phototherapy within 2 weeks * Open wounds or evidence of secondary infection at test sites * Pregnant or breastfeeding women * Multiple nevi, tattoos, dense body hair in the test areas * Debilitated or immunocompromised subjects * Known or suspected hypersensitivity to the interventional product (or its ingredients) or petrolatum * Refusal or failure to comply with the schedule of visits at the test site.

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Conditions

The condition(s) this trial relates to.

atopic eczema contact dermatitis injury psoriasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Atopic dermatitis Contact dermatitis Psoriasis Xerosis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • VMV Skin Research Center & Clinics

    RECRUITING

    Makati City, National Capital Region, 1229, Philippines

More trials for these conditions

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