New magnesium membrane could boost dental implant success

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Eligible are healthy patients that have the need for at least one dental implant. Specific inclusion criteria are: Inclusion Criteria: 1. Obtained informed consent from the patient, patients voluntarily signing the informed consent form before study related actions including patient's acceptance of the scheduled program of clinical and radiographic analysis 2. The patient shall be at least 18 years of age, male or female and have passed cessation of growth 3. Patients asking for more than one dental implant and presenting one site with a healed site (class h1i, h2i; h3i, v1i, c1i, h1e, h2e, h3e, Cologne Classification of Alveolar Ridge Defects (CCARD) requiring a GBR procedure prior to implant placement. 4. The teeth at the implant site must have been extracted or lost at least 8 weeks before the date of bone augmentation (volumetrically healed site) Exclusion Criteria: Systemic exclusion criteria 1. Major systemic diseases (e.g. recent myocardial infarction, cerebrovascular accident or valvular prosthesis surgery, a poorly stabilized diabetes mellitus, severe hypertension, severe peripheral artery occlusive disease, malignancies, autoimmune diseases, or kidney diseases, untreated or uncontrolled periodontal disease, uncontrolled drug or alcohol abuse, uncontrolled psychiatric disorders) 2. Acute infectious diseases 3. Immunocompromised patients 4. Serious disturbances of bone metabolism and/or serious bone diseases of endocrine etiology 5. Due to judgement of the principal investigator: Medical conditions requiring prolonged use of steroids and/or on-going treatment with gluco- and mineralocorticoids and with agents affecting calcium metabolism (e.g. calcitonin), and/or anti-coagulative therapy 6. Previous or current use of antiresorptive medication (e.g. bisphosphonates) 7. Previous oral / maxillofacial radiotherapy 8. Heavy smoker (definition: \>10 cigarettes per day) 9. Currently pregnant or breastfeeding women 10. Health conditions, which do not permit the surgical treatment Local exclusion criteria 1. Acute local inflammation or untreated periodontitis 2. Insufficient oral hygiene 3. Regenerative periodontal treatment necessary adjacent to the planned study site of interest 4. Mucosal diseases or oral white or ulcerative lesions (e.g. lichen planus, leukoplakia) 5. History of head and neck irradiation therapy 6. Severe bruxism or clenching or other destructive habits 7. Previous socket preservation, GBR or guided tissue regeneration (GTR) treatment at the implant site 8. Infections in tissue and adjacent tissue of the planned implantation site 9. Known hypersensitivity to any of the trace elements 10. Edentulous cases