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New hope for endometriosis sufferers: drug trial targets pelvic pain

NCT ID NCT07260669

Symptom relief Sponsor: Gesynta Pharma AB Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Sep 11, 2026 · Updated 1 time

Summary

This study tests a new drug called vipoglanstat to see if it can reduce pelvic pain in people with endometriosis. About 190 women aged 18 to 44 with moderate to severe pain will take either the drug or a placebo for four months. The goal is to find a better treatment option for this painful condition.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

About 190 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2025

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 44 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Premenopausal females 18 to \< 45 years of age at the time of Visit 1. * Endometriosis diagnosis confirmed and documented within the last 10 years prior to Visit 1 or during Visit based on: * Surgical (via direct visualization or biopsy verified) or * Imaging (ie, endometriotic lesion(s) detected by transvaginal sonography or magnetic resonance imaging \[MRI\]. * History of NMPP significantly affecting daily life confirmed at Visit 1. * The participant reports moderate, severe, or very severe pain during non-menstrual days in the month prior to Visit 2, based on patient global assessment NMPP. Exclusion Criteria: * Chronic pelvic pain that is not judged to be primarily related to endometriosis (eg, chronic pelvic infection, interstitial cystitis, nerve entrapments or neuropathies, non-endometriosis-related pelvic adhesive disease, persistent symptomatic ovarian cyst \[eg, dermoid\], posttubal ligation, symptomatic hydrosalpinx, and vaginismus). * Has had more than 2 surgical procedures for endometriosis.

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Conditions

The condition(s) this trial relates to.

Dysmenorrhea endometriosis Pelvic Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Endometriosis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    39 sites in 7 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • A.O. San Martino Genova Universita di Genova

    RECRUITING

    Genova, 16132, Italy

  • Accellacare North London

    RECRUITING

    Northwood, HA6 2RN, United Kingdom

  • Accellacare Northamptonshire

    RECRUITING

    Corby, NN18 9EZ, United Kingdom

  • Accellacare South London

    RECRUITING

    Orpington, BR5 3QG, United Kingdom

  • Accellacare Warwickshire

    RECRUITING

    Coventry, CV3 4FJ, United Kingdom

  • Accellacare Yorkshire

    RECRUITING

    Bradford, BD18 3SA, United Kingdom

  • Aidport sp. Z o.o.

    RECRUITING

    Skorzewo, 60-185, Poland

  • Centrum Ginekologii Artemida

    RECRUITING

    Bialystok, 15-464, Poland

  • Centrum Medyczne Angelius Provita

    RECRUITING

    Katowice, 40-611, Poland

  • Centrum Medyczne Chodzki

    RECRUITING

    Lublin, 20-093, Poland

  • Debreceni Egyetem Klinikai Kozpont

    RECRUITING

    Debrecen, 4032, Hungary

  • Delta Health Care

    RECRUITING

    Bucharest, 014142, Romania

  • ETG JustMed

    RECRUITING

    Warsaw, 01-691, Poland

  • ETG Siedlce

    RECRUITING

    Siedlce, 08-110, Poland

  • Fakultni nemocnice Brno

    RECRUITING

    Brno, 62500, Czechia

  • Fakultni nemocnice Kralovske Vinohrady

    RECRUITING

    Prague, 100 34, Czechia

  • FemiClinic

    RECRUITING

    Sofia, 1700, Bulgaria

  • Genesys Fertility Center

    RECRUITING

    Bucharest, 012071, Romania

  • Guy's and St Thomas' NHS Foundation Trust

    RECRUITING

    London, SE1 7EH, United Kingdom

  • Gyncare MUDr. Michael Svec s.r.o.

    RECRUITING

    Pilsen, 32600, Czechia

  • Gynekologie MEDA s.r.o

    RECRUITING

    Brno, 60200, Czechia

  • In- Vivo Sp. z o. o.

    RECRUITING

    Bydgoszcz, 85-048, Poland

  • Lyulin Hospital

    RECRUITING

    Sofia, 1336, Bulgaria

  • MHAT Puls AD

    RECRUITING

    Blagoevgrad, 2700, Bulgaria

  • MedEnd

    RECRUITING

    Budapest, 1027, Hungary

  • Medico Praktyka Lekarska

    RECRUITING

    Krakow, 31315, Poland

  • NEUMED Gynekologicka Ambulance s.r.o.

    COMPLETED

    Olomouc, 77900, Czechia

  • NZOZ Medem

    RECRUITING

    Katowice, 40-301, Poland

  • NZOZ Vita Longa Sp. z o.o.

    RECRUITING

    Katowice, 40-748, Poland

  • Norfolk and Norwich University Hospital - Norfolk and Norwich University Hospitals NHS Foundation Trust

    RECRUITING

    Norwich, NR4 7UY, United Kingdom

  • Prywatna Klinika Polozniczo - Ginekologiczna Sp. Z O.O.

    RECRUITING

    Bialystok, 15-224, Poland

  • Robert Karoly Private Hospital Tritonlife Medical Center

    RECRUITING

    Budapest, 1134, Hungary

  • SC Centrul Medical Unirea SRL

    RECRUITING

    Târgu Mureş, 540139, Romania

  • SC Centrul Medical Unirea SRL - Regina Maria

    RECRUITING

    Iași, 700023, Romania

  • STELLA-GYN, s.r.o.

    COMPLETED

    Vodňany, 38901, Czechia

  • Semmelweis Egyetem II. Sz. Szuleszeti es Nogyogyaszati Klinika

    COMPLETED

    Budapest, 1082, Hungary

  • Somogy Varmegyei Kaposi Mor Oktato Korhaz (Kaposi Mor County Hospital)

    COMPLETED

    Kaposvár, 7400, Hungary

  • Southampton General Hospital - University Hospital Southampton NHS Foundation Trust

    RECRUITING

    Southampton, SO16 6YD, United Kingdom

  • Southmead Hospital - North Bristol NHS Trust

    COMPLETED

    Bristol, BS10 5NB, United Kingdom

  • Specjalistyczna Praktyka Lekarska Krzysztof Dynowski

    RECRUITING

    Warsaw, 00-144, Poland

  • Spitalul Clinic Filantropia

    RECRUITING

    Bucharest, Romania

  • Spitalul Clinic Judetean de Urgenta Targu-Mures

    RECRUITING

    Târgu Mureş, 540136, Romania

  • Twoja Przychodnia SCM

    RECRUITING

    Szczecin, 71-500, Poland

  • University of Oxford

    RECRUITING

    Oxford, OX3 9DU, United Kingdom

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