Tiny study aims to map normal brain pressure for future headache relief
NCT ID NCT03948971
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study measures the normal blood pressure inside the brain's veins in 10 people who are already having a brain angiogram for other reasons. The goal is to create a baseline of healthy pressures, which can help doctors better understand and treat Idiopathic Intracranial Hypertension (IIH), a condition that causes severe headaches and vision problems. Participants do not need any extra visits or procedures.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 10 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2020
- Expected to finish
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May 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Candidates for elective cerebral arteriography Exclusion Criteria: * All patients with active, or a history of, intracranial venous pathology (arteriovenous malformation, arteriovenous fistulae, idiopathic intracranial hypertension, venous sinus thrombosis). * Patients with severe daily headaches or symptoms of idiopathic intracranial hypertension will also be excluded. * Body mass index \> 35. * Known diagnosis of heart failure or pulmonary hypertension. * Pregnant women will be excluded due to the radiation risk associated with Angiogram and Venogram.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Wake Forest Univesity Health Sciences
RECRUITINGWinston-Salem, North Carolina, 27157, United States
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