Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

C-Section drug showdown: norepinephrine beats phenylephrine for stable blood pressure

NCT ID NCT07327320

Disease control Sponsor: Tam Anh Research Institute Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compared two medications, norepinephrine and phenylephrine, given continuously during C-sections to prevent dangerously low blood pressure. 98 women participated. Norepinephrine was more effective, causing low blood pressure in only 14.9% of cases compared to 42.6% with phenylephrine, and also led to steadier heart rates. Both drugs were safe for the babies.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
norepinephrine and phenylephrine
What this could lead to
If confirmed, this could lead to a preferred drug for preventing low blood pressure during C-sections, improving safety and comfort for mothers.
What could go wrong
This is a single, small Phase 4 trial. Results may not apply to all hospitals or patients, and long-term effects were not studied.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

100 people

The number who actually took part.

Started

Jun 2024

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Parturients aged ≥18 years * Classified as American Society of Anesthesiologists physical status II * Term singleton pregnancies * Scheduled for elective CD under SA Exclusion Criteria: * Refusal to participate. * Fetal anomalies or suspected fetal compromise * Preeclampsia or eclampsia * Conversion to general anesthesia or use of labor analgesia * Contraindication to SA * Preexisting cardiovascular or cerebrovascular disease; chronic hypertension * Baseline bradycardia * Current use of cardiovascular or antihypertensive medications * Body mass index more than 40 kg/m² * Body weight less than 50 kg or more than 100 kg

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Anesthesia are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

hypotensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anesthesia Cesarean section Controlled hypotension for nasal surgeries Hypotension, controlled SPINAL

Contacts and locations

Locations

  • Tam Anh TP. Ho Chi Minh General Hospital

    Ho Chi Minh City, Ho Chi Minh, 700000, Vietnam

More trials for these conditions

Other studies related to the condition(s) this trial covers.